pharmacology
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Network pharmacology: the next paradigm in drug discoveryThe dominant paradigm in drug discovery is the concept of designing maximally selective ligands to act on individual drug targets.
Topix.net | 30-Apr-2012 18:20
Medco Study Finds Many Patients on Newer Oncology Treatments Are at Risk for Drug Interactions
But new research shows that many patients using these oral medications are also on other drugs that may prevent patients from getting the full benefit from their cancer treatment, or increase the risk of side effects.A The study by the Medco Research Institutea , the research subsidiary of Medco Health Solutions, Inc.
Topix.net | 16-Mar-2012 14:16
Population-based severity, onset and type of drug-drug interactions in prescriptions.
Methods and findings in experimental and clinical pharmacology , Vol. 32, No. 4. , pp.
Topix.net | 13-Mar-2012 23:42
Pharmacodynamic and pharmacokinetic drug interactions reported to...
European journal of clinical pharmacology , Vol. 67, No. 6. , pp. 633-641, doi:10.1007/s00228-010-0979-y Drug interactions resulting in adverse drug reactions represent a major health problem both for individuals and the community.
Topix.net | 09-Mar-2012 00:29
FDA Alert: Grapefruit & Medications, A Dangerous Mix
If you are taking Allegra, Lipitor, or other over-the-counter and prescription medicines, think twice before consuming these drugs along with grapefruit juice.
Topix.net | 27-Feb-2012 17:04
Clinical Pharmacology Advice Network opens in Avon Park
At Clinical Pharmacology Advice Network, Clinicial Pharmacology consultant Dennis Mungall will use his expertise in assisting patients as well as clinicians on a number of topics.
Topix.net | 22-Jan-2012 17:12
Exacerbation of Acetaminophen Hepatotoxicity by the Anthelmentic Drug Fenbendazole
Potential interactions between fenbendazole and hepatotoxicants such as acetaminophen are unknown, and this was investigated in this study.
Topix.net | 21-Jan-2012 01:50
Evaluation of warfarin drug interaction listings in US product...
Background: Because interactions with warfarin represent a serious risk to patients, drug information sources used by clinicians should contain accurate, timely, and practical drug interaction information.
Topix.net | 15-Oct-2011 20:12
Spaulding Clinical Announces Strategic Partnership with Clinigene...
Clinigene International Limited and Spaulding Clinical Research, LLC announced a strategic partnership agreement.
Topix.net | 29-Aug-2011 21:47
Spaulding Clinical Announces Strategic Partnership with Clinigene...
This partnership establishes a reliable, trustworthy, and cost-efficient global footprint for clinical pharmacology services providing an opportunity for both organizations to engage pharmaceutical clients strategically and accelerate First-In-Human to Proof-of-Concept clinical development.
Topix.net | 22-Aug-2011 19:42
PPD Names Jasmine (Jisong) Cui Chief Scientific Officer of BioDuro
PPD, Inc. today announced it has appointed Jasmine Cui, Ph.D., as chief scientific officer of BioDuro, A PPD Company.
Topix.net | 17-Aug-2011 04:09
Effect of tempol on renal cyclooxygenase expression and activity in experimental diabetes in the rat.
The Journal of pharmacology and experimental therapeutics , Vol. 314, No. 2. , pp.
Topix.net | 16-Aug-2011 21:55
Diversity goal of new University of South Alabama College of Medicine posts
In an effort to enroll a more diverse group of students and satisfy an accrediting agency's mandate, two doctors have stepped into new jobs at the University of South Alabama College of Medicine.
Topix.net | 16-Aug-2011 16:35
Receptor for Activated Protein Kinase C1 Regulates Cell Proliferation ...
From the Departments of Pharmacology and Chemical Biology , University of Pittsburgh School of Medicine, Pittsburgh, PA; Department of Obstetrics and Gynecology , University Hospital Zurich, Zurich, Switzerland.
Topix.net | 16-Aug-2011 10:16
Role of Perivascular Adipose Tissue-Derived Methyl Palmitate in...
From the Departments of Ophthalmology and Research , Buddhist Tzu Chi General Hospital, Hualien, Taiwan; Department of Medicine and Life Sciences , Institutes of Medical Sciences and Pharmacology and Toxicology , and Center for Vascular Medicine, College of Life Sciences , Tzu Chi University, Hualien, Taiwan; and Department of Pharmacology, ... (more)
Topix.net | 16-Aug-2011 06:06
UMaine president Paul Ferguson in his office at Alumni Hall Thursday, Aug. 11, 2011.
University of Maine President Paul Ferguson has a lot of questions just two weeks before the start of his first semester at the school.
Topix.net | 16-Aug-2011 01:52
Right Step and Dominion Diagnostics Joining Forces for More than Test Results
Right Step and its new partner for fast and accurate drug testing solutions, Dominion Diagnostics, are hosting "lunch and learn" tutorials.
Topix.net | 14-Aug-2011 03:03
Synthetic Chromanol Derivatives and Their Interaction with Complex...
601, Marianao 13, Ciudad Habana, Cuba Institute of Pharmacology and Toxicology, Department of Biomedical Sciences, University of Veterinary Medicine , Veterin rplatz 1, A-1210 Vienna, Austria Department of Chemistry, University of Natural Resources and Life Sciences , Muthgasse 18, A-1190 Vienna, Austria Laboratory of Microbiology, Parasitology and ...
Topix.net | 13-Aug-2011 03:16
Comparative Evaluation of HERG Currents and QT Intervals following...
Journal of Pharmacology and Experimental Therapeutics , Vol. 316, No. 3. , pp. 1098-1106. Key: citeulike:9521990 Posts Export Citation Likes Abstract The purpose of the present study was to comparatively evaluate human HERG currents and QT intervals following challenge with suspected torsadogenic and nontorsadogenic drugs.
Topix.net | 12-Aug-2011 21:51
Perturbation of Mitosis through Inhibition of Histone...
To whom correspondence should be addressed at Department of Toxicology, Institute of Pharmacology and Toxicology, University of Wurzburg, Versbacher Strasse 9, 97078 Wurzburg, Germany.
Topix.net | 12-Aug-2011 11:22
ALS: Focus on purinergic signalling
Pharmacology & Therapeutics , Vol. 132, No. 1. , pp. 111-122. Key: citeulike:9486462 Posts Export Citation Likes Abstract Amyotrophic lateral sclerosis is one of the most common neuromuscular diseases.
Topix.net | 12-Aug-2011 07:08
UNC-Duke Ties Lead To Collaborative Finding About Cell Division And Metabolism
Cells are the building blocks of the human body. They are a focus of scientific study, because when things go wrong at the cellular and molecular level the consequences for human health are often significant.
Topix.net | 10-Aug-2011 17:38
Using Genome-Wide Association Studies to Identify Genes Important in Serious Adverse Drug Reactions
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Topix.net | 10-Aug-2011 13:34
Medical management of paraquat ingestion.
British journal of clinical pharmacology Key: citeulike:9638506 Posts Export Citation Likes Abstract Poisoning by paraquat herbicide is a major medical problem in parts of Asia while sporadic cases occur elsewhere.
Topix.net | 10-Aug-2011 09:34
Targeting the Prostaglandin F2I Receptor for Preventing Preterm Labor with Azapeptide Tocolytics
Department of Pharmacology and Therapeutics, McGill University , Montr al H3G 1Y6, Qu bec, Canada D partement de Pharmacologie and D partement de Chimie, Universit de Montr al , Montr al H3C 3J7, Qu bec, Canada , Montr al H3T 1C5, Qu bec, Canada DOI: 10.1021/jm200608k Publication Date : July 20, 2011 Phone: +1 514 343 7339 .
Topix.net | 10-Aug-2011 05:24
[Perspective] 2-Adrenergic Receptor Polymorphisms and Signaling: Do...
Sci. Signal. , 9 August 2011 Vol. 4 , Issue 185, p. pe37 [DOI: 10.1126/scisignal.2002352] PERSPECTIVES I22-Adrenergic Receptor Polymorphisms and Signaling: Do Variants Influence the "Memory" of Receptor Activation? Paul A. Insel * Departments of Pharmacology and Medicine, University of California at San Diego, La Jolla, CA 92093, USA.
Topix.net | 10-Aug-2011 01:05
Agonist-selective patterns of A -opioid receptor phosphorylation...
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Topix.net | 09-Aug-2011 09:30
Spaulding Clinical Announces New Joint Partnership for Global Studies ...
Eurofins Optimed Clinical Research, an experienced European clinical research service provider and Spaulding Clinical Research, LLC., US-based, leading-edge Clinical Pharmacology, Cardiac Core Lab, and Medical Device Manufacturer, announce a joint partnership agreement.
Topix.net | 09-Aug-2011 01:11
New avenues for cell metabolism may have implications for many diseases
London, August 8 : UNC and Duke scientists' collaborative finding about cell division and metabolism may have implications for diseases ranging from neurodegenerative disorders like Parkinson's and Alzheimer's disease to certain types of cancers.
Topix.net | 08-Aug-2011 21:07
Battle of the dons over internet link to autism as scientists claim PCs 'shorten attention span'
A neuroscientist has sparked a war of words after suggesting a link between increased internet use and autism.
Topix.net | 08-Aug-2011 13:57
Effects of Levosimendan on Cardiac Gene Expression Profile and...
Tags Effects of Levosimendan on Cardiac Gene Expression Profile and Post-Infarct Cardiac Remodelling in Diabetic Goto-Kakizaki Rats.
Topix.net | 08-Aug-2011 12:57
UNC-Duke ties lead to collaborative finding about cell division & metabolism
Cells are the building blocks of the human body. They are a focus of scientific study, because when things go wrong at the cellular and molecular level the consequences for human health are often significant.
Topix.net | 07-Aug-2011 21:14
David Wylie goes from Lanark Grammar pupil to Edinburgh University professor
A BOYHOOD interest in science when he was a pupil at Lanark Grammar School has, 30 years later, led to David Wylie acquiring the highly impressive title of Professor of Ion Physiology and Pharmacology at Edinburgh University.
Topix.net | 07-Aug-2011 12:15
Pharmacology of commonly used analgesics and sedatives in the ICU:...
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Topix.net | 07-Aug-2011 07:00
Selective O-Desulfation Produces Nonanticoagulant Heparin that...
Journal of Pharmacology and Experimental Therapeutics , Vol. 282, No. 1. , pp. 208-219. Key: citeulike:9618793 Posts Export Citation Likes Abstract Heparin has potential use as an antiinflammatory treatment in many lung diseases but its therapeutic use is limited by inherent anticoagulant activity.
Topix.net | 06-Aug-2011 22:41
Inhibitor of Apoptosis Proteins as Novel Targets in Inflammatory Processes [Vascular Biology]
From the Munich Center for System-Based Drug Research, Department of Pharmacy and the Walter-Brendel-Center of Experimental Medicine , University of Munich, Munich, Germany; Institute of Experimental Immunology and Hepatology , University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Rudolf-Buchheim-Institute of Pharmacology , University of ...
Topix.net | 05-Aug-2011 14:27
Oxidized Low-Density Lipoprotein Activates p66Shc via Lectin-Like...
From the Cardiovascular Research, Institute of Physiology, and Center for Integrative Human Physiology, University of ZA1 4rich, Switzerland ; Department of Cardiology, Cardiovascular Center, University Hospital, ZA1 4rich, Switzerland ; Cardiology, Department of Clinical and Molecular Medicine, University La Sapienza of Rome, Sant'Andrea Hospital, ...
Topix.net | 05-Aug-2011 10:28
DrugBank 3.0: a comprehensive resource for 'omics' research on drugs.
Nucleic acids research , Vol. 39, No. Database issue. , pp. D1035-D1041. Key: citeulike:8222585 Posts Export Citation Likes Abstract DrugBank is a richly annotated database of drug and drug target information.
Topix.net | 04-Aug-2011 10:15
Research Scientist II - Molecular Pharmacology
Doing well by doing good. What if every day you could work, dream, share and grow while contributing to the discovery of life-saving medicines? Where everyone not only has a say, but is rewarded for speaking up? Where each day feels more like an experience than a job? Where quality of life is a way of life, and passion is always tangible? We invite ...
Topix.net | 04-Aug-2011 06:01
10: Virtual hospital teaches students Watch
A virtual hospital ward is helping pharmacology students learn how to keep an eye on patient health.
Topix.net | 04-Aug-2011 01:46
MOE holds talks to enhance education ties with Malaysia
Taiwan hopes that discussions with Malaysia on the recognition of university and college degrees issued in Taiwan will be successfully concluded by September, Minister of Education Wu Ching-ji said.
Topix.net | 03-Aug-2011 20:32
Immunohistochemical comparison of differentiation markers on paraffin ...
Tags Immunohistochemical comparison of differentiation markers on paraffin and plastic embedded human bone samples.
Topix.net | 03-Aug-2011 02:43
Revealing Secrets of RNA
The ability to tag proteins with a green fluorescent light to watch how they behave inside cells so revolutionized the understanding of protein biology that it earned the scientific teams who developed the technique Nobel Prizes in 2008.
Topix.net | 02-Aug-2011 13:09
'Facebook, Twitter leading to identity crisis'
According to Baroness Greenfield, professor of pharmacology at Oxford University, social networking websites have created a generation obsessed with themselves, having short attention spans and a child-like desire for constant feedback on their lives LONDON, UK: Social networking websites Facebook and Twitter have created a generation obsessed with ...
Topix.net | 02-Aug-2011 09:05
Controlled and Cardiac-Restricted Overexpression of the Arginine...
Controlled and Cardiac-Restricted Overexpression of the Arginine Vasopressin V1A Receptor Causes Reversible Left Ventricular Dysfunction Through GI q-Mediated Cell Signaling From the Center For Translational Medicine, Department of Medicine , Division of Biostatistics, Department of Pharmacology and Experimental Therapeutics , Jefferson Medical ...
Topix.net | 02-Aug-2011 01:46
Facebook and Twitter creating vain self-obsessed people with child-like need for feedback
Facebook and Twitter have created a generation obsessed with themselves, who have short attention spans and a childlike desire for constant feedback on their lives, a top scientist believes.
Topix.net | 31-Jul-2011 07:05